The Wales Infants’ and ChildreN’s Genome Service (WINGS) is available for acutely unwell children with a likely underlying genetic cause. This test is currently only available on a trio basis. This means the child and BOTH parents must have samples taken. Alternative rapid genetic testing is available if only one parent is present. Currently WINGS is only available for inpatients.
To initiate WINGS please contact the on call Genetics team. It is very unlikely a request without prior discussion with the Clinical Genetics team will be processed. Due to the nature of the test, we ask for the referrer to be a Consultant, Registrar, Nurse Practitioner/Specialist or equivalent.
Please contact the AWMGS on 02921 842577 (Monday-Friday 9am-5pm) to discuss any child you think may be eligible for WINGS.
Essential Criteria for WINGS
1. Suspected underlying monogenic cause.
2. DNA sample is available from both parents and they are willing to consent to testing.
3. A timely genetic diagnosis (within 2-3 weeks) may significantly alter the clinical management of the patient.
4. The imminent demise of the patient is unlikely – if the clinical condition is worsening and death is likely, other testing strategies may be more appropriate. Please bank DNA (ideally before any blood transfusions) and contact Clinical Genetics to discuss.
High Priority Criteria for WINGS
1. There is no obvious single genetic test to do from the presenting phenotype.
2. The patient presents with a likely genetic disorder, but specific diagnostic tests available for that phenotype have failed to arrive at a diagnosis or are not accessible within a reasonable timeframe.
Please click here for the referral pack, which contains a clinical pathway checklist, request forms, consent forms (x3, one for each family member taking part), and a patient information leaflet.
WINGS Request Form (editable copy).
WINGS Service Information Sheet
Frequently Asked Questions
The AWMGS also has an 'on call' service (using the same contact number above) if you would like a patient to be reviewed on the ward or if you have any other urgent clinical questions.